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Antigenic Specificity | Rat CTSL / Cathepsin L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody recognizes the mature form of Cathepsin L (25 kD) from human, mouse and rat origins. Reactivity to other species has not been tested. Rat kidney tissue lysate can be used as a positive control. Cathepsin L (CTSL1) is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. |
Immunogen | Immunogen Description: Synthetic peptide surrounding amino acid 223 of rat Cathepsin L. |
Other Names | [CTSL / Cathepsin L IHC-plus; CTSL; Cathepsin L; Cathepsin L1; CATL; CTSL1; Major excreted protein; MEP; Rat CTSL; Cathepsin L], [CTSL; CTSL; MEP; CATL; CTSL1; CTSL1; MEP] |
Gene, Accession # | [CTSL], Gene ID: 1514, NCBI: NP_001903.1, UniProt: P07711 |
Catalog # | MBS246830 |
Price | $530 |
Order / More Info | Rat CTSL / Cathepsin L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |