Cardif (Human) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCardif (Human)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsImmunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionRecognizes human cardif. Detects a band of ~65kDa by Western blot. RIG-I (retinoic acid-inducible gene I; Ddx58) and Mda5 (melanoma differentiation-associated gene 5, also known as Ifih1 or Helicard) are proteins that sense viral replication intermediates, such as double-stranded RNA and triggers the host antiviral programs. These molecules signal the downstream activation of NF-kappaB and IFN regulatory factor (IRF) -3, which coordinately regulate the expression of type-I interferons. Cardif (also called VISA/IPS-1/MAVS) is a CARD (caspase activation and recruitment domain)-containing adaptor protein that interacts with the CARD domain of RIG-I and Mda5, leading to the activation of NF-kappaB and IRF3. Cardif is located to the mitochondria
ImmunogenImmunogen: Recombinant human Cardif (CARD adapter inducing interferon- beta ) (aa 160-450).
Other Names[CARD adapter inducing interferon- beta; IPS-1; Interferon- beta promoter stimulator protein 1; MAVS; Mitochondrial antiviral signalling protein; VISA; Virus-induced signalling adapter], [MAVS; MAVS; IPS1; VISA; IPS-1; CARDIF; IPS1; KIAA1271; VISA; MAVS; Cardif; IPS-1; VISA]
Gene, Accession #Gene ID: 57506, NCBI: Q7Z434.2, UniProt: Q7Z434
Catalog #MBS565363
Price$500
Order / More InfoCardif (Human) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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