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Antigenic Specificity | Human CD41 |
Clone | [HIP8] |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD41 is a 125/25 kD alpha subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbalpha) and light chain (gpIIbbeta) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin. |
Immunogen | n/a |
Other Names | [Integrin alpha-Iib; ITGA2B; GPalpha Iib; GPIIb; Platelet membrane glycoprotein Iib; CD41; GP2B; ITGAB] |
Gene, Accession # | [CD41], Gene ID: 3674, NCBI: NP_000410.2, UniProt: P08514 |
Catalog # | MBS2556892 |
Price | $100, $125, $165 |
Order / More Info | Human CD41 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Denzin L, et al. 1996. J. Exp. Med. 184:2153. 2. Denzin L, et al. 1995. Cell 82:155. 3. Riberdy J, et al. 1994. J. Cell Biol. 125:1225. |