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Antigenic Specificity | CHK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHK2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, a checkpoint kinase ATM phosphorylates and activates Chk2, which in turn phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer. |
Immunogen | Immunogen: Polyclonal Chk2 antibody, Anti-Chk2 antibody, Chk-2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human CHK2, different from the related rat and Rabbit sequences by one amino acid, as the immunogen |
Other Names | [Affinity Purified Rabbit CHK2; Chk2; Chk2; CHK 2; CHK2; CHK-2; Chk-2; CHK 2; CHK-2] |
Gene, Accession # | [CHK2], Gene ID: 11200 |
Catalog # | MBS5312608 |
Price | $345 |
Order / More Info | CHK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |