Human Receptor-interacting serine/threonine-protein kinase 3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Receptor-interacting serine/threonine-protein kinase 3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionEssential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
ImmunogenImmunogen: Recombinant human Receptor-interacting serine/threonine-protein kinase 3 protein (1-120aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47368 / sc-135171
Other Names[RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3; RIPK3; RIP3], [RIPK3; RIPK3; RIP3; RIP3; RIP-3]
Gene, Accession #[RIPK3], Gene ID: 11035, NCBI: NP_006862.2, UniProt: Q9Y572
Catalog #MBS1494303
Price$120, $160
Order / More InfoHuman Receptor-interacting serine/threonine-protein kinase 3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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