Tyk2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTyk2
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionTyk2 (tyrosine kinase 2), with 1187-amino acid protein (about 131kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines. IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.
ImmunogenImmunogen: Purified recombinant fragment of Tyk2 expressed in E. Coli.
Other Names[JTK1], [TYK2; TYK2; JTK1; IMD35]
Gene, Accession #[Tyk2], Gene ID: 7297, NCBI: NP_003322.3, UniProt: P29597
Catalog #MBS850296
Price$280
Order / More InfoTyk2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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