Edit |   |
Antigenic Specificity | FASN |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Fatty acid synthase(FASN) detection. Tested with WB, IHC-P in Human. Background: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. |
Immunogen | Immunogen: E Coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively. Ig Type: Rabbit IgG |
Other Names | [Fatty acid synthase; [Acyl-carrier-protein] S acetyltransferase; [Acyl-carrier-protein] S malonyltransferase; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; Enoyl-[acyl-carrier-protein] reductase; FAS; FAS_HUMAN; FASN; Fatty acid synthase; MGC14367; MGC15706; OA 519; Oleoyl-[acyl-carrier-protein] hydrolase; SDR27X1; Short chain dehydrogenase/reductase family 27X member 1; fatty acid synthase], [FASN; FASN; FAS; OA-519; SDR27X1; FAS] |
Gene, Accession # | [FASN], Gene ID: 2194, NCBI: NP_004095.4, UniProt: P49327 |
Catalog # | MBS177671 |
Price | $315 |
Order / More Info | FASN Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: FASN fatty acid synthase. 2. Jayakumar A, Tai MH, Huang WY, al-Feel W, Hsu M, Abu-Elheiga L, Chirala SS, Wakil SJ (Oct 1995). Human fatty acid synthase: properties and molecular cloning. Proc Natl Acad Sci U S A 92 (19): 8695-9. 3. Smith S, Witkowski A, Joshi AK (July 2003). Structural and functional organization of the animal fatty acid synthase. Prog. Lipid Res. 42 (4): 289-317. |