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Antigenic Specificity | KREMEN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Three isoforms of KREMEN1 exists as a result of alternative splicing event. KREMEN1 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and tempora |
Immunogen | Immunogen: Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1. Buffer: KREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [KREMEN1; KRM1; KREMEN; KRM1; Kremen protein 1; Dickkopf receptor; kringle containing transmembrane protein 1], [KREMEN1; KREMEN1; KRM1; KREMEN; KREMEN; KRM1] |
Gene, Accession # | [KREMEN1], Gene ID: 83999, NCBI: NP_114434, UniProt: Q96MU8 |
Catalog # | MBS153356 |
Price | $375 |
Order / More Info | KREMEN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |