FASTK (C-term), 395-424 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FASTK (C-term), 395-424 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This FASTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human FASTK. The protein encoded by this gene is a member of theserine/threonine protein kinase family. This kinase was shown to beactivated rapidly during Fas-mediated apoptosis in Jurkat cells. Inresponse to Fas receptor ligation, it phosphorylates TIA1, anapoptosis-promoting nuclear RNA-binding protein. The encodedprotein is a strong inducer of lymphocyte apoptosis. Two transcriptvariants encoding different isoforms have been found for this gene.Other variants exist, but their full-length natures have not yetbeen determined. |
| Immunogen | n/a |
| Other Names | [Fas-activated serine/threonine kinase; FAST kinase; FASTK] |
| Gene, Accession # | [FASTK], Gene ID: 10922, NCBI: NP_001245390.1, UniProt: Q14296 |
| Catalog # | MBS9205090 |
| Price | $165, $370 |
| Order / More Info | FASTK (C-term), 395-424 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Simarro, M., et al. J. Immunol. 184(9):5325-5332(2010) de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009) Simarro, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(27):11370-11375(2007) Wu, C., et al. Proteomics 7(11):1775-1785(2007) Izquierdo, J.M., et al. J. Biol. Chem. 282(3):1539-1543(2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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