Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) Antibody from MYBIOSOURCE INC.

Search, find, compare suppliers for anti-Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) antibody, protein, ELISA kits.

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Antigenic SpecificityGlypican-3 (GPC3) (Hepatocellular Carcinoma Marker)
Clone[GPC3/1534R]
Host SpeciesRabbit
Reactive Specieshuman, rat.
IsotypeIgG
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor. In patients with HCC, GPC3 is overexpressed in neoplastic liver tissue and elevated in serum, but is undetectable in normal liver, benign liver, and the serum of healthy donors. GPC3 expression is also found to be higher in HCC liver tissue than in cirrhotic liver or liver with focal lesions such as dysplastic nodules and areas of hepatic adenoma (HA) with malignant transformation. In the context of testicular germ cell tumors, GP
ImmunogenImmunogen: Recombinant full-length human GPC3 protein. Cellular Localization: Cytoplasmic
Other Names[DGSX; Glypican proteoglycan 3; GPC3; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI-5; MXR7; OCI-5; SDYS; Secreted glypican-3; SGBS1], [GPC3; GPC3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; OCI5]
Gene, Accession #[GPC3], Gene ID: 2719, NCBI: NP_001158089.1, UniProt: P51654
Catalog #MBS439997
Price$190, $340, $340
Order / More InfoGlypican-3 (GPC3) (Hepatocellular Carcinoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYan, B., et al. 2011. Expression and clinicopathologic significance of glypican 3 in hepatocellular carcinoma. Ann. Diagn. Pathol. 15: 162-169.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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