Claudin 7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityClaudin 7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: porcine, bovine, horse, sheep, rabbit, dog
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Claudin 7 Antibody detects endogenous levels of Claudin 7. Description: Plays a major role in tight junction-specific obliteration of the intercellular space.Post Translational Modifications: Phosphorylated.Subunit Structure: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity). The phosphorylated form interacts with EPCAM (PubMed:16054130). Does not interact with CD81 (PubMed:20375010).Similarity: Belongs to the claudin family.
ImmunogenImmunogen: A synthesized peptide derived from human Claudin 7. Tissue Specificity: Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occur
Other Names[CEPTR L2; CEPTRL 2; CEPTRL2; Claudin 1; Claudin 9; Claudin-7; Claudin1; Claudin7; Claudin9; CLD7_HUMAN; CLDN 7; CLDN-7; Clostridium perfringens enterotoxin receptor like 2; CPETR L2; CPETRL 2; CPETRL2; Hs.84359]
Gene, Accession #[CLDN7], Gene ID: 1366, NCBI: NP_001171951.1, UniProt: O95471
Catalog #MBS9611241
Price$225, $280, $340
Order / More InfoClaudin 7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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