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Antigenic Specificity | Claudin 7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: porcine, bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Claudin 7 Antibody detects endogenous levels of Claudin 7. Description: Plays a major role in tight junction-specific obliteration of the intercellular space.Post Translational Modifications: Phosphorylated.Subunit Structure: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity). The phosphorylated form interacts with EPCAM (PubMed:16054130). Does not interact with CD81 (PubMed:20375010).Similarity: Belongs to the claudin family. |
Immunogen | Immunogen: A synthesized peptide derived from human Claudin 7. Tissue Specificity: Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occur |
Other Names | [CEPTR L2; CEPTRL 2; CEPTRL2; Claudin 1; Claudin 9; Claudin-7; Claudin1; Claudin7; Claudin9; CLD7_HUMAN; CLDN 7; CLDN-7; Clostridium perfringens enterotoxin receptor like 2; CPETR L2; CPETRL 2; CPETRL2; Hs.84359] |
Gene, Accession # | [CLDN7], Gene ID: 1366, NCBI: NP_001171951.1, UniProt: O95471 |
Catalog # | MBS9611241 |
Price | $225, $280, $340 |
Order / More Info | Claudin 7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |