Edit |   |
---|---|
Antigenic Specificity | IL-33 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry-Paraffin (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-33 Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1α/beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-κB and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromati |
Immunogen | Immunogen: IL-33 antibody was raised against a 19 amino acid synthetic peptide from near the center of human IL-33. The immunogen is located within amino acids 150 - 200 of IL-33. Buffer: IL-33 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; NFHEV; Interleukin-33; Interleukin-1 family member 11; IL-33; interleukin 33], [IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV] |
Gene, Accession # | [IL33], Gene ID: 90865, NCBI: NP_254274, UniProt: O95760 |
Catalog # | MBS150331 |
Price | $375 |
Order / More Info | IL-33 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |