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Antigenic Specificity | KLF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus intr |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 20 amino acid peptide near the carboxy terminus of human KLF4. |
Other Names | [Kruppel-like factor 4, GKLF, EZF] |
Gene, Accession # | [KLF4], Gene ID: 9314, NCBI: AAH30811 |
Catalog # | MBS9400857 |
Price | $320 |
Order / More Info | KLF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |