ULBP1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityULBP1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against ULBP1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also cau
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ULBP1
Other Names[UL16-binding protein 1 isoform 1; NKG2D ligand 1; UL16-binding protein 1; UL16 binding protein 1; ALCAN-beta; Retinoic acid early transcript 1I; UL16-binding protein 1]
Gene, Accession #[ULBP1], Gene ID: 80329, NCBI: NP_079494, UniProt: Q9BZM6
Catalog #MBS3209708
Price$365
Order / More InfoULBP1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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