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Antigenic Specificity | ULBP1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against ULBP1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also cau |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ULBP1 |
Other Names | [UL16-binding protein 1 isoform 1; NKG2D ligand 1; UL16-binding protein 1; UL16 binding protein 1; ALCAN-beta; Retinoic acid early transcript 1I; UL16-binding protein 1] |
Gene, Accession # | [ULBP1], Gene ID: 80329, NCBI: NP_079494, UniProt: Q9BZM6 |
Catalog # | MBS3209708 |
Price | $365 |
Order / More Info | ULBP1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |