Edit |   |
Antigenic Specificity | Human INTERLEUKIN-1RA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml after reconstitution |
Applications | ELISA (EIA), Functional Assays (FN), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product specifically recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1.. . Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease. This product specifically recognises human Interleukin-1 receptor antagonist (IL-1RA), a natural |
Immunogen | Immunogen: Recombinant human IL-1RA Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human IL-1RA were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [interleukin-1 receptor antagonist protein isoform 3; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist protein; IL1 inhibitor; IL1RN (IL1F3); intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); type II interleukin-1 receptor antagonist; interleukin 1 receptor antagonist; ICIL-1RA; IL1 inhibitor; INN: Anakinra], [IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP] |
Gene, Accession # | Gene ID: 3557, NCBI: NP_000568.1, UniProt: P18510 |
Catalog # | MBS224241 |
Price | $550 |
Order / More Info | Human INTERLEUKIN-1RA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |