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Antigenic Specificity | Human Poly [ADP-ribose] polymerase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing. |
Immunogen | Immunogen: Recombinant human Poly [ADP-ribose] polymerase 3 protein (294-533aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30625 / sc-130838 / sc-133887 |
Other Names | [PARP-3; hPARP-3; ADP-ribosyltransferase diphtheria toxin-like 3; ARTD3; IRT1; NAD(+) ADP-ribosyltransferase 3; ADPRT-3; Poly[ADP-ribose] synthase 3; pADPRT-3; PARP3; ADPRT3; ADPRTL3], [PARP3; PARP3; IRT1; ARTD3; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3; ADPRT3; ADPRTL3; PARP-3; hPARP-3; ARTD3; ADPRT-3; pADPRT-3] |
Gene, Accession # | [PARP3], Gene ID: 10039, NCBI: NP_001003931.3, UniProt: Q9Y6F1 |
Catalog # | MBS1499093 |
Price | $120, $160 |
Order / More Info | Human Poly [ADP-ribose] polymerase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |