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Antigenic Specificity | LIG3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 730-1009 of human LIG3 (NP 039269.2). |
Other Names | [LIG2; LIG3alpha] |
Gene, Accession # | [LIG3], Gene ID: 3980, NCBI: P49916.2, UniProt: P49916 |
Catalog # | MBS8549069 |
Price | $280 |
Order / More Info | LIG3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |