LCK (C-term), 480-509 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLCK (C-term), 480-509
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB)
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DescriptionThis LCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 amino acids from the C-terminal region of human LCK. LCK is a member of the Src family of protein tyrosine kinases (PTKs). This protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
Immunogenn/a
Other Names[Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK; LCK]
Gene, Accession #[LCK], Gene ID: 3932, NCBI: NP_001036236.1, UniProt: P06239
Catalog #MBS9200994
Price$165, $370
Order / More InfoLCK (C-term), 480-509 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPaster,W., J. Immunol. 182 (4), 2160-2167 (2009) Ngai,J., Eur. J. Immunol. 38 (11), 3208-3218 (2008) Strasner,A.B., J. Immunol. 181 (5), 3706-3713 (2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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