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Antigenic Specificity | Cytokeratin, pan (Epithelial Marker) |
Clone | [SPM115 + SPM116] |
Host Species | Mouse |
Reactive Species | human, monkey, cow, dog, rabbit, mouse, rat, chicken |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize t |
Immunogen | Immunogen: Human epidermal keratin |
Other Names | [K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39], [KRT76] |
Gene, Accession # | [KRT77], Gene ID: 374454, NCBI: NP_778253.2, UniProt: Q7Z794 |
Catalog # | MBS438464 |
Price | $190, $340, $340 |
Order / More Info | Cytokeratin, pan (Epithelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Tseng SCG et. al. Cell 1982; 30361. Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8 |