CLSTN1 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CLSTN1 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against CLSTN1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: CLSTN1 induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, CLSTN1 stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment,CLSTN1 abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent trans |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLSTN1 |
| Other Names | [calsyntenin-1 isoform 1; Calsyntenin-1; calsyntenin-1; calsyntenin 1; Alcadein-alpha; Alc-alpha; Alzheimer-related cadherin-like protein; Non-classical cadherin XB31alphaCleaved into the following 2 chains:Soluble Alc-alpha; SAlc-alphaCTF1-alpha; Alternative name(s):; C-terminal fragment 1-alpha] |
| Gene, Accession # | [CLSTN1], Gene ID: 22883, NCBI: NP_001009566, UniProt: O94985 |
| Catalog # | MBS3207444 |
| Price | $365 |
| Order / More Info | CLSTN1 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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