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Antigenic Specificity | CYP7B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.6mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CYP7B1 protein. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or H |
Immunogen | Immunogen: Synthetic peptide of human CYP7B1 Immunogen Type: Peptide |
Other Names | [CP7B; CBAS3; SPG5A] |
Gene, Accession # | [CYP7B1], Gene ID: 9420, NCBI: NP_004811, UniProt: O75881 |
Catalog # | MBS9429961 |
Price | $255 |
Order / More Info | CYP7B1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |