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Antigenic Specificity | STAT3 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
Immunogen | Immunogen: This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human. |
Other Names | [APRF; HIES; ADMIO; ADMIO1] |
Gene, Accession # | [STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763 |
Catalog # | MBS8558681 |
Price | $280 |
Order / More Info | STAT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |