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Antigenic Specificity | PPAR DELTA (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chimpanzee (expected from sequence), mouse (expected from sequence), rabbit (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects peroxisome proliferator-activated receptor, delta (PPARD), a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. . . PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta.. . PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis. MB |
Immunogen | Immunogen: Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to PPAR delta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [peroxisome proliferator-activated receptor delta; Peroxisome proliferator-activated receptor delta; peroxisome proliferator-activated receptor delta; PPARdelta/beta; Peroxisome proliferator-activated receptor beta; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; peroxisome proliferator activator receptor delta; Nuclear hormone receptor 1; NUC1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; PPAR-beta], [Ppard; Ppard; NUC1; NUC-1; Nr1c2; Pparb; PPAR[b]; Pparb/d; PPAR-beta; PPARdelta; PPAR-delta; Nr1c2; Pparb; PPAR-delta; NUC1; PPAR-beta] |
Gene, Accession # | [PPAR DELTA], Gene ID: 19015, NCBI: NP_035275.1, UniProt: P35396 |
Catalog # | MBS221543 |
Price | $375 |
Order / More Info | PPAR DELTA (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |