GAD2 (Center), 109-138 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GAD2 (Center), 109-138 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, porcine, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.47 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2. This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantibody and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Alternative splicing results in multiple transcript variants that |
| Immunogen | n/a |
| Other Names | [Glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform; GAD2; GAD65] |
| Gene, Accession # | [GAD2], Gene ID: 2572, NCBI: NP_000809.1, UniProt: Q05329 |
| Catalog # | MBS9214425 |
| Price | $165, $370 |
| Order / More Info | GAD2 (Center), 109-138 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) : Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) : Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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