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Antigenic Specificity | THRAP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: THRAP3 antibody detects endogenous levels of total THRAP3. Function: Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and it |
Immunogen | Immunogen: A synthesized peptide derived from human THRAP3 Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (100%), Sheep (100%), Dog (100%) |
Other Names | [FLJ22082; Thrap3; Thyroid hormone receptor associated protein 3; Thyroid hormone receptor-associated protein 3; Thyroid hormone receptor-associated protein complex 150 kDa component; Thyroid hormone receptor-associated protein complex; TR150_HUMAN; Trap150] |
Gene, Accession # | [THRAP3], Gene ID: 9967, NCBI: NP_001308400.1, UniProt: Q9Y2W1 |
Catalog # | MBS9609210 |
Price | $240, $280 |
Order / More Info | THRAP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |