ATM Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ATM |
| Clone | 1D1 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ATM protein detects endogenous levels of ATM. The protein encoded by ATM (ATM serine/threonine kinase) belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in ATM are associated with ataxia telangiectasia, an autosomal recessive disorder. |
| Immunogen | Immunogen: Recombinant Protein of ATM of ATM |
| Other Names | [Mouse ATM Mouse (1D1)] |
| Gene, Accession # | [ATM], Gene ID: 472, NCBI: AAI37170.1, UniProt: Q13315 |
| Catalog # | MBS9700559 |
| Price | $130, $220, $325 |
| Order / More Info | ATM Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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