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Antigenic Specificity | ATP2C1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least four isoforms of ATP2C1 are known to exist; this antibody will recognize only the three longest isoforms. ATP2C1 antibody will not cross-react with ATP2C2. ATP2C1, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder characterized by persistent blisters and erosions of the skin. Unlike the related protein ATP2C2, ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher app |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 19 amino acid peptide near the carboxy terminus of human ATP2C1. |
Other Names | [Calcium-transporting ATPase type 2C member 1, ATP2C1A, HHD, BCPM, PMR1, SPCA1, hSPCA1] |
Gene, Accession # | [ATP2C1], Gene ID: 27032, NCBI: NP_001001486 |
Catalog # | MBS9401987 |
Price | $320 |
Order / More Info | ATP2C1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |