Mouse CD274 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Mouse CD274 |
| Clone | [MIH6] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.25 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse CD274 antibody, clone MIH6 detects mouse CD274, also known as B7-H1 and PD-1L, a single pass type I cell membrane glycoprotein, a member of the B7 family of co-stimulatory molecules. CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells (Ishada et al. 2002), endothelial cells (Eppihimer et al. 2002) and epithelial cells in response to Interferons alpha, beta and gamma. CD274 is reported to possess dual functions; inhibition of activated effector T cells and co-stimulation of na?ve T cells (Selenko-Gebauer et al. 2003). CD274 inhibits proliferation of activated T cells via ligation to the co-inhibitory molecule CD279 (programmed death-1; PD-1) leading to the secretio |
| Immunogen | n/a |
| Other Names | [programmed cell death 1 ligand 1; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; PDCD1 ligand 1; programmed death ligand 1; CD274 antigen; B7 homolog 1; B7-H1; CD_antigen: CD274], [Cd274; Cd274; B7h1; Pdl1; Pdcd1l1; Pdcd1lg1; A530045L16Rik; B7h1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1] |
| Gene, Accession # | [CD274], Gene ID: 60533, NCBI: NP_068693.1, UniProt: Q9EP73 |
| Catalog # | MBS216273 |
| Price | $430 |
| Order / More Info | Mouse CD274 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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