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Antigenic Specificity | ARG |
Clone | [BC-3] |
Host Species | Mouse |
Reactive Species | human, rat, cat, cow, dog, guinea pig, horse, porcine, rabbit, sheep. |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 0.1 mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the aggrecanase (ADAMTS-1, -4 & -5)-generated N-terminal neoepitope ARG after cleavage between amino acids EGE and ARG within the interglobular domain of aggrecanase-catabolised aggrecan (Human aggrecan sequence enumeration). This antibody will not recognize the sequence ARG if it is in the non-cleaved intact aggrecan protein core; i.e. it will only recognize the aggrecanase generated neoepitope ARG. Aggrecan monoclonal antibody to N-terminal neoepitope ARG (mouse, clone BC-3). Aggrecan degradation products containing this neoepitope are rapidly released from the tissue in model explant culture systems and are also present in the synovial fluids of patients with degenerative joint disease. Overview: During differentiation |
Immunogen | Immunogen: ARGSV synthetic peptide conjugate. Myeloma: x63-Ag8.653. Light Chain Type: kappa |
Other Names | [Aggrecan, N-terminal neoepitope ARG], [ACAN; ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP; AGC1; CSPG1; MSK16; CSPCP] |
Gene, Accession # | Gene ID: 176, NCBI: AAH36445.1, UniProt: P16112 |
Catalog # | MBS442018 |
Price | $435 |
Order / More Info | ARG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |