PUMA (CT) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PUMA (CT) antibody, protein, ELISA kits.
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| Antigenic Specificity | PUMA (CT) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.025 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~23kDa. Detects ~16kDa bands sometimes, possibly corresponding to PUMAbeta. Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 up-regulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse (1-3). PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta (1). PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c relea |
| Immunogen | Immunogen: C-terminal amino acids of human PUMA Immunogen Species: Human |
| Other Names | [Rabbit Human PUMA (CT); BBC3; BCL2 binding component 3; p53 up regulated modulator of apoptosis; PUMA/JFY1] |
| Gene, Accession # | [PUMA], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH3 |
| Catalog # | MBS8002010 |
| Price | $240 |
| Order / More Info | PUMA (CT) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nakano K., Vousden K.H. (2001) Mol Cell. 2001; 7(3): 683-94. 2. Yu J., Zhang L., Hwang P.M., Kinzler K.W., Vogelstein B. (2001) Mol Cell. 7(3): 673-82. 3. Han J., et al. (2001) Proc Natl Acad Sci U S A. 98(20): 11318-23. |
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MYBIOSOURCE INC.
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