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Antigenic Specificity | TNFRSF14 NT (Tumor necrosis factor receptor superfamily 14) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-κB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for contr |
Immunogen | Immunogen: Rabbit polyclonal TNFRSF14 antibody was raised against a 15 amino acid peptide from near the amino terminus of human TNFRSF14 |
Other Names | [Tumor necrosis factor receptor superfamily 14; Herpesvirus], [TNFRSF14; TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; HVEA; HVEM; Herpesvirus entry mediator A; HveA; TR2] |
Gene, Accession # | Gene ID: 8764, NCBI: NP_003811.2, UniProt: Q92956 |
Catalog # | MBS395601 |
Price | $510 |
Order / More Info | TNFRSF14 NT (Tumor necrosis factor receptor superfamily 14) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |