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Antigenic Specificity | Mouse Semaphorin 4A |
Clone | [8B27] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Neutralization |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling |
Immunogen | n/a |
Other Names | [semaphorin-4A; Semaphorin-4A; semaphorin-4A; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; Semaphorin-B; Sema B], [Sema4a; Sema4a; SemB; Semab; AI132332; Semab; SemB; Sema B] |
Gene, Accession # | Gene ID: 20351, NCBI: NP_001156961.1, UniProt: Q62178 |
Catalog # | MBS692456 |
Price | $490 |
Order / More Info | Mouse Semaphorin 4A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |