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Antigenic Specificity | HSPA9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using HSPA9 antibody. Immunofluorescence analysis of U2OS cell using HSPA9 antibody. Blue: DAPI for nuclear staining. Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat-inducible (1, 2). This protein is essential for transporting many mitochondrial proteins from the cytoplasm to mitochondria (3). Grp75 inactivates the tumor suppressor p53 (4). Studies found that Grp75 is overexpressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation (5). Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts (6). |
Immunogen | Immunogen: Recombinant protein of human HSPA9 |
Other Names | [HSPA9 protein, partial; Stress-70 protein, mitochondrial; stress-70 protein, mitochondrial; heat shock protein family A (Hsp70) member 9; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74], [HSPA9; HSPA9; CSA; MOT; MOT2; SAAN; CRP40; EVPLS; GRP75; PBP74; GRP-75; HSPA9B; SIDBA4; MTHSP75; HEL-S-124m; GRP75; HSPA9B; mt-HSP70; GRP-75; MOT; PBP74] |
Gene, Accession # | [HSPA9], Gene ID: 3313, NCBI: AAH30634.1 |
Catalog # | MBS419450 |
Price | $385 |
Order / More Info | HSPA9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |