TICAM2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTICAM2
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescat, human, monkey, porcine
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.60-0.65 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionAffinity Purified TIRAP3b long form Antibody. Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 140-170 on human TIRAP3b long form protein. Expression: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1).
Other Names[Putative NF-kappa-B-activating protein 502; TICAM2; TIR containing adapter molecule 2; TIR domain containing adaptor protein; TIR domain-containing adapter molecule 2; TIRAP3; TIRP; Toll-like receptor adaptor protein 3; Toll/interleukin-1 receptor domain-containing protein; TRAM; TRIF-related adapter molecule], [TMED7-TICAM2; TICAM2; TIRAP3; TIRP; TRAM; TICAM-2; MyD88-4]
Gene, Accession #[TICAM2], Gene ID: 100302736, NCBI: AAQ97430.1, UniProt: Q86XR7
Catalog #MBS540667
Price$390
Order / More InfoTICAM2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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