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Antigenic Specificity | TICAM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cat, human, monkey, porcine |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.60-0.65 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified TIRAP3b long form Antibody. Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 140-170 on human TIRAP3b long form protein. Expression: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1). |
Other Names | [Putative NF-kappa-B-activating protein 502; TICAM2; TIR containing adapter molecule 2; TIR domain containing adaptor protein; TIR domain-containing adapter molecule 2; TIRAP3; TIRP; Toll-like receptor adaptor protein 3; Toll/interleukin-1 receptor domain-containing protein; TRAM; TRIF-related adapter molecule], [TMED7-TICAM2; TICAM2; TIRAP3; TIRP; TRAM; TICAM-2; MyD88-4] |
Gene, Accession # | [TICAM2], Gene ID: 100302736, NCBI: AAQ97430.1, UniProt: Q86XR7 |
Catalog # | MBS540667 |
Price | $390 |
Order / More Info | TICAM2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |