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Antigenic Specificity | Human CRADD / RAIDD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Gibbon, dog, gorilla, human, orangutan. predicted reactivity: monkey, hamster (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects an ~24 kD protein, corresponding to the apparent molecular mass of RAIDD on SDS-PAGE immunoblots. This 24 kD band, as well as a 67 kD band, can be specifically inhibited by the relevant peptide. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. |
Immunogen | Immunogen Description: A 15 residue synthetic peptide (C)NSSPSDRQINQLAQR based on the human RAIDD (residues 112-126) (1) with the cysteine (C) residue added and the peptide coupled to KLH. |
Other Names | [CRADD / RAIDD IHC-plus; CRADD; Death adaptor molecule RAIDD; RAIDD; MRT34; Human CRADD; RAIDD], [RAIDD] |
Gene, Accession # | [CRADD], Gene ID: 8738, NCBI: NP_003796.1, UniProt: P78560 |
Catalog # | MBS247377 |
Price | $530 |
Order / More Info | Human CRADD / RAIDD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |