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Antigenic Specificity | CBLB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CBLB protein. The Casitas B lineage lymphoma (Cbl) proteins (in mammals these are c-Cbl, Cbl-b, and Cbl-c) are a family of single subunit RING finger protein-ubiquitin E3 ligases that contain multiple protein interaction motifs (1). All Cbl proteins have a highly conserved N-terminal tyrosine kinase-binding (TKB) domain that mediates interactions between Cbl proteins and phosphorylated tyrosine residues on Cbl substrates. C-terminal to the RING finger, Cbl proteins have proline-rich domains that mediate interactions with SH3 domain-containing proteins. Phosphorylated tyrosine residues mediate interactions with SH2 domain-containing proteins such as the p85 subunit of PI3K. These protein-protein |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CBLB. |
Other Names | [Cbl-b; RNF56; Nbla00127] |
Gene, Accession # | [CBLB], Gene ID: 868, NCBI: NP_733762.2, UniProt: Q13191 |
Catalog # | MBS9404538 |
Price | $255 |
Order / More Info | CBLB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |