CD8b Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD8b |
| Clone | [341] |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 0.05 mg |
| Concentration | 500 ug/ml |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 341 monoclonal antibody reacts with rat CD8beta. CD8beta is a member of the immunoglobulin superfamily which heterodimerizes with CD8 alpha to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8beta expression is absent in athymic mice, which are populated by T-cells expressing CD8 alpha homodimers. This has led to the idea that CD8beta expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck. |
| Immunogen | n/a |
| Other Names | [Mouse CD8b (FITC); CD8b; CD8b; CD 8b; Ly-3; CD-8b; CD-8b; CD8 beta; CD8b; CD 8b] |
| Gene, Accession # | [CD8b], Gene ID: 926, NCBI: AAI00912.1 |
| Catalog # | MBS5309301 |
| Price | $215 |
| Order / More Info | CD8b Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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