GDNF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGDNF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene m
ImmunogenImmunogen: Recombinant protein of human GDNF (NP 000505.1).
Other Names[glial cell line-derived neurotrophic factor isoform 5; Glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor; glial cell derived neurotrophic factor; Astrocyte-derived trophic factor]
Gene, Accession #[GDNF], Gene ID: 2668, NCBI: NP_001265027.1, UniProt: P39905
Catalog #MBS8569422
Price$280
Order / More InfoGDNF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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