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Antigenic Specificity | Ldlrap1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Ldlrap1. It was validated on Western BlotTarget Description: Ldlrap1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). It may be required for LDL binding and internalization but not for receptor clustering in coated pits. It may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. Ldlrap1 may also be involved in the internalization of other LDLR family members. Ldlrap1 binds to phosphoinositides |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Ldlrap1 |
Other Names | [low density lipoprotein receptor adapter protein 1; Low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adaptor protein 1; Autosomal recessive hypercholesterolemia protein homolog] |
Gene, Accession # | [LDLRAP1], Gene ID: 100017, NCBI: NP_663529, UniProt: Q8C142 |
Catalog # | MBS3212150 |
Price | $335 |
Order / More Info | Ldlrap1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |