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Antigenic Specificity | JMJD2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | JMJD2A Antibody: Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. The first member of this group, JMJD2A, is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. JMJD2A can also form a complex with the androgen receptor (AR), a transcription factor that is pivotal for the development of prostate cancer. Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity, suggesting that JMJD2A might be a critical protein with roles in ce |
Immunogen | Immunogen: JMJD2A antibody was raised against a 14 amino acid synthetic peptide from near the center of human JMJD2A. Buffer: JMJD2A Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [JMJD2A; JMJD2; JHDM3A; JMJD2A; TDRD14A; JMJD2; KIAA0677; Lysine-specific demethylase 4A; JmjC domain-containing histone demethylation protein 3A; lysine (K)-specific demethylase 4A], [KDM4A; KDM4A; JMJD2; JHDM3A; JMJD2A; TDRD14A; JHDM3A; JMJD2; JMJD2A; KIAA0677] |
Gene, Accession # | [KDM4A], Gene ID: 9682, NCBI: CAH71021, UniProt: O75164 |
Catalog # | MBS150247 |
Price | $375 |
Order / More Info | JMJD2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |