ASK1 (MEKK5/MAP3K5) (S966), 944-973 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityASK1 (MEKK5/MAP3K5) (S966), 944-973
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis ASK1(MEKK5/MAP3K5) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 944-973 amino acids from human ASK1(MEKK5/MAP3K5). Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in
Immunogenn/a
Other Names[Mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; MAP3K5; ASK1; MAPKKK5; MEKK5]
Gene, Accession #[MAP3K5], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683
Catalog #MBS9204406
Price$165, $370
Order / More InfoASK1 (MEKK5/MAP3K5) (S966), 944-973 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMin,W.,Circ. Res. 102 (7), 840-848 (2008) Li,X.,Cell Death Differ. 15 (4), 739-750 (2008) Noguchi,T.,J. Biol. Chem. 283 (12), 7657-7665 (2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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