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Antigenic Specificity | MEK2 (MAP2K2) (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MEK2 (MAP2K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MEK2 (MAP2K2). MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax. |
Immunogen | n/a |
Other Names | [Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2; MAP2K2; MEK2; MKK2; PRKMK2] |
Gene, Accession # | [MAP2K2], Gene ID: 5605, NCBI: NP_109587.1, UniProt: P36507 |
Catalog # | MBS9201177 |
Price | $165, $370 |
Order / More Info | MEK2 (MAP2K2) (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Burroughs, K.D., et al., Mol. Cancer Res. 1(4):312-322 (2003). Tran, H., et al., Mol. Cell. Biol. 23(20):7177-7188 (2003). Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003). Li, Y., et al., J. Biol. Chem. 278(16):13663-13671 (2003). Liu, X., et al., J. Biol. Chem. 277(42):39312-39319 (2002). |