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Antigenic Specificity | Human ANDROGEN RECEPTOR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chimpanzee (expected from sequence), rhesus monkey (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 1 mL |
Concentration | IgG concentration 5.0 mg/ml |
Applications | Immunohistology Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human Androgen Receptor antibody recognizes the human Androgen Receptor (AR) also known as the Dihydrotestosterone receptor or Nuclear receptor subfamily 3 group C member 4. Dihydrotestosterone (DHT) binds with highest affinity to AR and together with testosterone promotes AR transcriptional activity thereby ensuring the development and maintenance of male reproductive functions. AR homodimers recruit a variety of factors including coactivators and mediator proteins whose enzymatic activities promote chromatin remodeling and transcriptional regulation of target genes leading to cell differentiation, survival, and proliferation. Mutated AR is strongly implicated in development of prostate adenocarcinoma and metastases development |
Immunogen | n/a |
Other Names | [androgen receptor isoform 1; Androgen receptor; androgen receptor; androgen nuclear receptor variant 2; dihydrotestosterone receptor; nuclear receptor subfamily 3 group C member 4; androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4], [AR; AR; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; DHTR; NR3C4] |
Gene, Accession # | Gene ID: 367, NCBI: NP_000035.2, UniProt: P10275 |
Catalog # | MBS220616 |
Price | $375 |
Order / More Info | Human ANDROGEN RECEPTOR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |