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Antigenic Specificity | Caspase-3(P17) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Caspase-3(CASP3) detection. Tested with WB, IHC-P in Mouse, Rat. Background: CASP3(Caspase3 Apoptosis-Related Cysteine Protease), also known as YAMA, CPP32 or APOPAIN, is a caspase protein that interacts with caspase 8 and caspase 9. It is encoded by the CASP3 gene. The CASP3 protein is a member of the cysteine-aspartic acid protease(caspase) family. Tiso et al.(1996) used radiation hybrid mapping to localize the CPP32 gene to human chromosome 4q33-q35.1. Fernandes-Alnemri et al.(1994) found that overexpression of CPP32 in insect cells induced apoptosis. Coexpression of the 2 CPP32 subunits in insect cells also resulted in apoptosis. Tewari et al.(1995) showed that purified human ICE cleaved t |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse Caspase-3 (P17) (67-81aa TDVDAANLRETFMGL), different from the related rat sequence by one amino acid. |
Other Names | [Caspase-3; caspase 3, apoptosis-related cysteine peptidase; A830040C14Rik; Apopain; Apopain precursor; CASP 3; CASP-3; CASP3; Casp3a; Caspase 3; Caspase 3 apoptosis related cysteine protease; Caspase 3 p17 subunit; Caspase 3, apoptosis-related cysteine peptidase; Caspase 3, apoptosis-related cysteine protease; Caspase 3, apoptosis-related cysteine protease a; Caspase-3 subunit p17; Caspase3; CC3; CPP 32; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; Human cysteine protease CPP32 isoform alpha mRNA complete cds; ICE3; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SCA1; SREBP cleavage activity 1; Yama; Yama protein], [Casp3; Casp3; CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Apopain; Caspase-3; A830040C14Rik; Cpp32; CASP-3; CPP-32; SCA-1] |
Gene, Accession # | [CASP3], Gene ID: 12367, NCBI: P70677.1, UniProt: P70677 |
Catalog # | MBS176189 |
Price | $315 |
Order / More Info | Caspase-3(P17) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |