Noggin Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Noggin antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | Noggin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Noggin, also known as NOG, is a protein which in humans is encoded by the NOG gene which maps to chromosome 17q22. [1] Noggin binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP4). By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily, noggin may have a principal role in creating morphogenic gradients. [2] It plays a key role in neural induction by inhibiting BMP4, along with other TGF-beta signaling inhibitors such as chord in and follistatin. |
| Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of Noggin. |
| Other Names | [Noggin], [NOG; NOG; SYM1; SYNS1] |
| Gene, Accession # | Gene ID: 9241, NCBI: NP_005441.1, UniProt: Q13253 |
| Catalog # | MBS355051 |
| Price | $275 |
| Order / More Info | Noggin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Valenzuela, D. M., Economides, A. N., Rojas, E., Lamb, T. M., Nunez, L., Jones, P., Ip, N. Y., Espinosa, R., III, Brannan, C. I., Gilbert, D. J., Copeland, N. G., Jenkins, N. A., Le Beau, M. M., Harland, R. M., Yancopoulos, G. D. Identification of mammalian noggin and its expression in the adult nervous system. J. Neurosci. 15: 6077-6084, 1995. 2. Gong, Y., Krakow, D., Marcelino, J., Wilkin, D., Chitayat, D., Babul-Hirji, R., Hudgins, L., Cremers, C. W., Cremers, F. P. M., Brunner, H. G., Reinker, K., Rimoin, D. L., Cohn, D. H., Goodman, F. R., Reardon, W., Patton, M., Francomano, C. A., Warman, M. L. Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis. Nature Genet. 21: 302-304, 1999. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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