EPS15 (C-term), 840-870 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | EPS15 (C-term), 840-870 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This EPS15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 840-870 amino acids from the C-terminal region of human EPS15. EPS15 is involved in cell growth regulation, possibly via the regulation of mitogenic signals and control of cell proliferation. EPS15 also participates in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Potential interaction partners include AP2A2, STN2, EPN1, and CRK via its SH3-binding sites. EPS15 is ubiquitously expressed. Phosphorylation on Tyr-849 is involved in the internalization of EGFR. EPS15 is not required for membrane translocation after EGF treatment or for targeting to coated pits, but essential |
| Immunogen | n/a |
| Other Names | [Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p; EPS15; AF1P] |
| Gene, Accession # | [EPS15], Gene ID: 2060, NCBI: NP_001153441.1, UniProt: P42566 |
| Catalog # | MBS9207252 |
| Price | $165, $370 |
| Order / More Info | EPS15 (C-term), 840-870 Antibody from MYBIOSOURCE INC. |
| Product Specific References | de Beer, T., et al., Nat. Struct. Biol. 7(11):1018-1022 (2000). Enmon, J.L., et al., Biochemistry 39(15):4309-4319 (2000). de Beer, T., et al., Science 281(5381):1357-1360 (1998). Chen, H., et al., Nature 394(6695):793-797 (1998). Matsuda, M., et al., J. Biol. Chem. 271(24):14468-14472 (1996). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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