PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PAK1/PAK2/PAK3 (Ab-423/402/421) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total PAK1/PAK2/PAK3 protein. The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.421~425/400~404/419~423 (R-S-T-M-V) derived from Human PAK1/PAK2/PAK3. |
| Other Names | [p21-activated kinase 1; PAK-1; p65-PAK; Alpha-PAK] |
| Gene, Accession # | [PAK1/PAK2/PAK3], Gene ID: 5058, NCBI: NP_001122092.1, UniProt: Q13153 |
| Catalog # | MBS9407614 |
| Price | $200, $255 |
| Order / More Info | PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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