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Antigenic Specificity | VEGF-D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: EGF-D is most closely related to VEGF-C by virtue of the presence of N- and C-terminal extensions that are not found in other VEGF family members. In adult human tissues, VEGF-D mRNA is most abundant in heart, lung, skeletal muscle, colon, and small intestine. Analyses of VEGF-D receptor specificity revealed that VEGF-D is a ligand for both VEGF receptors (VEGFRs) VEGFR-2 (Flk1) and VEGFR-3 (Flt4) and can activate these receptors. However, VEGF-D does not bind to VEGFR-1. Expression of a truncated derivative of VEGF-D demonstrated that the receptor-binding capacities reside in the portion of the molecule that is most closely related in primary structure to other VEGF family members and that corresponds to the mature form of VEGF |
Immunogen | Immunogen: E. coli expressed human VEGF-D |
Other Names | [VEGFD; VEGF D; Vascular endothelial growth factor D; c-fos-induced growth factor; FIGF], [FIGF; VEGFD; VEGF-D] |
Gene, Accession # | [VEGF-D], Gene ID: 2277, NCBI: BAA24264.1, UniProt: D89630 |
Catalog # | MBS841149 |
Price | $150, $290 |
Order / More Info | VEGF-D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |