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Antigenic Specificity | RPB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rpb1 Polyclonal Antibody detects endogenous levels of Rpb1 protein. POLR2A encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. |
Immunogen | Immunogen: Synthesized peptide derived from human Rpb1 around the non-phosphorylation site of S1619 |
Other Names | [Rabbit Rpb1; POLR2A; POLR2; DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1] |
Gene, Accession # | [RPB1], Gene ID: 5430, NCBI: NP_000928.1, UniProt: P24928 |
Catalog # | MBS9703070 |
Price | $130, $220, $325 |
Order / More Info | RPB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |