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Antigenic Specificity | Human IRAK4 / IRAK-4 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | Bat, Gibbon, gorilla, horse, human, monkey. predicted reactivity: bovine, dog, porcine, rabbit, sheep (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human IRAK4. IRAK4, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK4 has auto- and cross-phosphorylation kinase activity and has been shown to phosphorylate and activate IRAK1. Additionally, IRAK4 interacts with IRAK1 and TRAF6 in an IL-1-dependent manner, and overexpression of IRAK4 can activate NF-kappaB as well as mitogen-activated protein (MAP) kinase pathways. |
Immunogen | Immunogen Description: Synthetic peptide NKPITPSTYVRC from the N-terminus of human IRAK4 (NP_057207.2; NP_001107654.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Bat, Horse, Lizard (100%). |
Other Names | [IRAK4 / IRAK-4 (N-Terminus) IHC-plus; IRAK4; IPD1; IRAK-4; NY-REN-64; REN64; Human IRAK4; IRAK-4], [IRAK-4] |
Gene, Accession # | [IRAK4], Gene ID: 51135, NCBI: NP_057207.2, UniProt: Q9NWZ3 |
Catalog # | MBS243919 |
Price | $530 |
Order / More Info | Human IRAK4 / IRAK-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |