Human IRAK4 / IRAK-4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IRAK4 / IRAK-4
Clonepolyclonal
Host SpeciesGoat
Reactive SpeciesBat, Gibbon, gorilla, horse, human, monkey. predicted reactivity: bovine, dog, porcine, rabbit, sheep (at least 90% immunogen sequence identity)
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration0.5 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Human IRAK4. IRAK4, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK4 has auto- and cross-phosphorylation kinase activity and has been shown to phosphorylate and activate IRAK1. Additionally, IRAK4 interacts with IRAK1 and TRAF6 in an IL-1-dependent manner, and overexpression of IRAK4 can activate NF-kappaB as well as mitogen-activated protein (MAP) kinase pathways.
ImmunogenImmunogen Description: Synthetic peptide NKPITPSTYVRC from the N-terminus of human IRAK4 (NP_057207.2; NP_001107654.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Bat, Horse, Lizard (100%).
Other Names[IRAK4 / IRAK-4 (N-Terminus) IHC-plus; IRAK4; IPD1; IRAK-4; NY-REN-64; REN64; Human IRAK4; IRAK-4], [IRAK-4]
Gene, Accession #[IRAK4], Gene ID: 51135, NCBI: NP_057207.2, UniProt: Q9NWZ3
Catalog #MBS243919
Price$530
Order / More InfoHuman IRAK4 / IRAK-4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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